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ULK1 抗体 (pSer556)

The 兔 单克隆 anti-ULK1 antibody is suitable to detect ULK1 in samples from 人. It has been validated for WB.
产品编号 ABIN7674408
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ULK1 抗体 (pSer556) (ABIN7674408)

抗原

See all ULK1 抗体
ULK1 (Unc-51 Like Kinase 1 (ULK1))

适用

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宿主

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克隆类型

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单克隆

标记

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This ULK1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

0
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    pSer556

    原理

    Phospho-ULK1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: Peptide

    Immunogen: peptide

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    ULK1 (Unc-51 Like Kinase 1 (ULK1))

    别名

    ULK1ULK1

    背景

    Synonyms: Serine/threonine-protein kinase ULK1|Autophagy-related protein 1 homolog (ATG1, hATG1)|Unc-51-like kinase 1|ULK1|KIAA0722

    Background: ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase(FAK) family interacting protein of 200 kDa(FIP 200)(PMID:21460634). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC(PMID:23573318).

    分子量

    140-150 kDa

    基因ID

    8408

    UniProt

    O75385

    途径

    Regulation of Cell Size, Autophagy
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