ULK1 抗体 (pSer556)
Quick Overview for ULK1 抗体 (pSer556) (ABIN7674408)
抗原
See all ULK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer556
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原理
- Phospho-ULK1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: Peptide
Immunogen: peptide
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- ULK1 (Unc-51 Like Kinase 1 (ULK1))
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别名
- ULK1ULK1
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背景
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Synonyms: Serine/threonine-protein kinase ULK1|Autophagy-related protein 1 homolog (ATG1, hATG1)|Unc-51-like kinase 1|ULK1|KIAA0722
Background: ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase(FAK) family interacting protein of 200 kDa(FIP 200)(PMID:21460634). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC(PMID:23573318).
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分子量
- 140-150 kDa
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基因ID
- 8408
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UniProt
- O75385
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途径
- Regulation of Cell Size, Autophagy
抗原
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