Integrin beta 7 抗体 (PerCP-Cy5.5)
Quick Overview for Integrin beta 7 抗体 (PerCP-Cy5.5) (ABIN7674298)
抗原
See all Integrin beta 7 (ITGB7) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- PerCP-Cy5.5 Anti-Human/Mouse Integrin β7 Antibody
-
纯化方法
- 0
-
纯度
- 0
-
亚型
- IgG2b, kappa
-
-
-
-
应用备注
- Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- 4 °C
-
储存方法
- 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)
-
有效期
- 12 months
-
-
- Integrin beta 7 (ITGB7)
-
别名
- Integrin beta7
-
背景
-
Synonyms: β7 Integrin|integrin βp|ITGB7
Background: Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.
-
分子量
- 0
-
基因ID
- 3695
-
UniProt
- P26010, P26011
-
途径
- Integrin Complex
抗原
-