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LAMP1 抗体 (PerCP-Cy5.5)

This anti-LAMP1 antibody is a 小鼠 单克隆 antibody detecting LAMP1 in FACS. Suitable for 人.
产品编号 ABIN7674207
发货至: 中国

Quick Overview for LAMP1 抗体 (PerCP-Cy5.5) (ABIN7674207)

抗原

See all LAMP1 抗体
LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This LAMP1 antibody is conjugated to PerCP-Cy5.5

应用范围

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Flow Cytometry (FACS)

克隆位点

H4A3
  • 原理

    PerCP-Cy5.5 Anti-Human CD107a Antibody

    纯化方法

    0

    纯度

    0

    亚型

    IgG1, kappa
  • 应用备注

    Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    4 °C

    储存方法

    2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

    别名

    CD107a

    背景

    Synonyms: LAMP-1LGP-120|Lysosome-Associated Membrane Protein 1|LAMP-1

    Background: CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.

    分子量

    0

    基因ID

    3916

    UniProt

    P11279

    途径

    Autophagy
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