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PD-1 抗体 (PE-Cy5.5)

This anti-PD-1 antibody is a 大鼠 单克隆 antibody detecting PD-1 in FACS. Suitable for 小鼠.
产品编号 ABIN7673970
发货至: 中国

Quick Overview for PD-1 抗体 (PE-Cy5.5) (ABIN7673970)

抗原

See all PD-1 (PDCD1) 抗体
PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

适用

  • 179
  • 96
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小鼠

宿主

  • 96
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  • 45
  • 13
  • 3
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  • 2
  • 2
  • 1
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大鼠

克隆类型

  • 183
  • 67
  • 5
单克隆

标记

  • 128
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  • 1
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  • 1
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This PD-1 antibody is conjugated to PE-Cy5.5

应用范围

  • 157
  • 82
  • 79
  • 52
  • 42
  • 19
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  • 1
  • 1
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Flow Cytometry (FACS)

克隆位点

29F-1A12
  • 原理

    PE-Cy5.5 Anti-Mouse CD279/PD-1 Antibody

    纯化方法

    0

    纯度

    0

    亚型

    IgG2a, kappa
  • 应用备注

    Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    4 °C

    储存方法

    2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

    别名

    CD279

    背景

    Synonyms: Programmed Death-1|PD-1

    Background: CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

    分子量

    0

    基因ID

    18566

    UniProt

    Q02242

    途径

    Cancer Immune Checkpoints
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