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IL-10 抗体 (PE)

This anti-IL-10 antibody is a 大鼠 单克隆 antibody detecting IL-10 in FACS. Suitable for 小鼠.
产品编号 ABIN7673754
发货至: 中国

Quick Overview for IL-10 抗体 (PE) (ABIN7673754)

抗原

See all IL-10 (IL10) 抗体
IL-10 (IL10) (Interleukin 10 (IL10))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This IL-10 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

JES5-16E3
  • 原理

    PE Anti-Mouse IL-10 Antibody

    免疫原

    interleukin 10

    亚型

    IgG2b, kappa
  • 应用备注

    Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    4 °C

    储存方法

    2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    IL-10 (IL10) (Interleukin 10 (IL10))

    别名

    IL-10

    背景

    Synonyms: Interleukin-10 (IL-10)|Cytokine synthesis inhibitory factor (CSIF)|IL10

    Background: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

    基因ID

    16153

    UniProt

    P18893

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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