CCR5 抗体 (PE)
Quick Overview for CCR5 抗体 (PE) (ABIN7673566)
抗原
See all CCR5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PE Anti-Human CD195 Antibody
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纯化方法
- 0
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纯度
- 0
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亚型
- IgG2a, kappa
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应用备注
- Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- 4 °C
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储存方法
- 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
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别名
- CD195
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背景
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Synonyms: 0
Background: CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CCR5 mediates an intracellular signal thought to induce cell differentiation and proliferation. CCR5 has also been shown to act as a co-receptor for R5 HIV-1 cell entry, modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
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分子量
- 0
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基因ID
- 1234
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UniProt
- P51681
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途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
抗原
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