MEF2C 抗体
Quick Overview for MEF2C 抗体 (ABIN7673464)
抗原
See all MEF2C 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MEF2C-Specific antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: Peptide
Immunogen: myocyte enhancer factor 2C
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亚型
- IgG
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anti-Myocyte Enhancer Factor 2C (MEF2C) (AA 1-125) antibody
MEF2C 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6H2G2 unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) antibodyMEF2C 适用: 人 WB, IHC, IF, IHC (p), ICC, IHC (fro), IP 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) (AA 170-380) antibodyMEF2C 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) antibodyMEF2C 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) (AA 365-394) antibodyMEF2C 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) (Ser59) antibodyMEF2C 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) (Ser396) antibodyMEF2C 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) (Ser396) antibodyMEF2C 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) (AA 170-380) antibodyMEF2C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2C (MEF2C) (AA 170-380) antibodyMEF2C 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- MEF2C (Myocyte Enhancer Factor 2C (MEF2C))
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别名
- MEF2C
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背景
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Synonyms: Myocyte-specific enhancer factor 2C|Myocyte enhancer factor 2C|MEF2C
Background: MEF2C belongs to the MEF2 family. It is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. It is crucial for normal neuronal development, distribution, and electrical activity in the neocortex and is necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. This protein is required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. It may also be involved in neurogenesis and in the development of cortical architecture. The immunogen used is peptide from the specific sequecne of MEF2C transcript variant 1 match to transcript variant 5. The antibody can recognize the transcript variant 1, transcript variant 2 and transcript variant 3 of MEF2C.
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分子量
- 51 kDa
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UniProt
- Q06413
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling
抗原
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