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IL-10 抗体

This anti-IL-10 antibody is a 兔 多克隆 antibody detecting IL-10 in WB 和 ELISA. Suitable for Hamster.
产品编号 ABIN7673400
发货至: 中国

Quick Overview for IL-10 抗体 (ABIN7673400)

抗原

See all IL-10 (IL10) 抗体
IL-10 (IL10) (Interleukin 10 (IL10))

适用

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Hamster

宿主

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克隆类型

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多克隆

标记

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This IL-10 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 原理

    Il10 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    interleukin 10

    亚型

    IgG
  • 应用备注

    WB: 1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    IL-10 (IL10) (Interleukin 10 (IL10))

    别名

    Il10

    背景

    Synonyms: Interleukin family protein|Il10|IL-10

    Background: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

    分子量

    21 kDa

    UniProt

    G3HB01

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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