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Haptoglobin 抗体 (AA 180-406)

This anti-Haptoglobin antibody is a 小鼠 单克隆 antibody detecting Haptoglobin in WB 和 ELISA. Suitable for 人 和 Pig.
产品编号 ABIN7673380
发货至: 中国

Quick Overview for Haptoglobin 抗体 (AA 180-406) (ABIN7673380)

抗原

See all Haptoglobin (HP) 抗体
Haptoglobin (HP)

适用

  • 115
  • 50
  • 44
  • 16
  • 13
  • 10
  • 10
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, Pig

宿主

  • 131
  • 31
  • 12
  • 8
  • 5
  • 2
小鼠

克隆类型

  • 148
  • 40
单克隆

标记

  • 108
  • 30
  • 10
  • 8
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Haptoglobin antibody is un-conjugated

应用范围

  • 138
  • 91
  • 49
  • 49
  • 41
  • 24
  • 19
  • 13
  • 13
  • 13
  • 12
  • 10
  • 10
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA

克隆位点

7C8
  • 抗原表位

    • 15
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 180-406

    原理

    HP antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 180-406aa

    Immunogen: haptoglobin

    亚型

    IgG2a
  • 应用备注

    WB: 1:2000 - 1:20000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Haptoglobin (HP)

    别名

    HP

    背景

    Synonyms: Haptoglobin|Zonulin|Haptoglobin alpha chain|Haptoglobin beta chain|HP

    Background: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial, Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.

    分子量

    42 kDa

    基因ID

    3240

    UniProt

    P00738

    途径

    Transition Metal Ion Homeostasis
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