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Haptoglobin 抗体 (Middle Region)

HP 适用: 人 WB, FACS, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN952678
发货至: 中国
  • 抗原 See all Haptoglobin (HP) 抗体
    Haptoglobin (HP)
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 299-326, Middle Region
    适用
    • 100
    • 44
    • 38
    • 14
    • 10
    • 10
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 114
    • 14
    • 10
    • 7
    • 7
    • 2
    克隆类型
    • 134
    • 19
    多克隆
    标记
    • 79
    • 28
    • 11
    • 10
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Haptoglobin antibody is un-conjugated
    应用范围
    • 108
    • 61
    • 60
    • 21
    • 19
    • 17
    • 14
    • 14
    • 13
    • 13
    • 13
    • 10
    • 10
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes Human Haptoglobin (Center).
    纯化方法
    Protein A column, followed by peptide affinity purification
    免疫原
    KLH conjugated synthetic peptide between 299-326 amino acids from the Central region of Human Haptoglobin Genename: HP
    亚型
    Ig Fraction
    Top Product
    Discover our top product HP Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Higham, Baker, Jackson, Shah, Lea, Singh: "Dysregulation of the CD163-Haptoglobin Axis in the Airways of COPD Patients." in: Cells, Vol. 11, Issue 1, (2022) (PubMed).

  • 抗原
    Haptoglobin (HP)
    别名
    Haptoglobin (HP 产品)
    别名
    HP antibody, wu:fb64e01 antibody, BP antibody, HP2ALPHA2 antibody, HPA1S antibody, HP-1 antibody, HPR antibody, Zonulin antibody, haptoglobin antibody, haptoglobin-like antibody, HP antibody, hp antibody, Hp antibody, LOC479668 antibody, LOC101102413 antibody
    背景
    This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.
    分子量
    45205 Da
    基因ID
    3240
    NCBI登录号
    NP_001119574
    途径
    Transition Metal Ion Homeostasis
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