ATG7 抗体
Quick Overview for ATG7 抗体 (ABIN7672901)
抗原
See all ATG7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- ATG7 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen: ATG7 autophagy related 7 homolog
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亚型
- IgG2a
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anti-ATG7 Autophagy Related 7 (ATG7) (AA 500-676) antibody
ATG7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 477-698) antibodyATG7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 540-569), (C-Term) antibodyATG7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7474 unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 22-51) antibodyATG7 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 494-523) antibodyATG7 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) antibodyATG7 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 558-703) antibodyATG7 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7D3E5 unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibodyATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (HRP)ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal HRP
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (FITC)ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC
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应用备注
- WB: 1:1000-1:5000, IHC: 1:50-1:200, IF: 1:20-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- ATG7 (ATG7 Autophagy Related 7 (ATG7))
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别名
- ATG7
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背景
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Synonyms: Ubiquitin-like modifier-activating enzyme ATG7|ATG12-activating enzyme E1 ATG7|Autophagy-related protein 7 (APG7-like, hAGP7)|Ubiquitin-activating enzyme E1-like protein|ATG7|APG7L
Background: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport(Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress. Plays also a key role in the maintenance of axonal homeostasis, the prevention of axonal degeneration, the maintenance of hematopoietic stem cells, the formation of Paneth cell granules, as well as in adipose differentiation.
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分子量
- 68-78 kDa
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基因ID
- 10533
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UniProt
- O95352
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途径
- Response to Water Deprivation, Autophagy
抗原
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