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Integrin beta 7 抗体 (APC)

This APC-conjugated 大鼠 单克隆 anti-Integrin beta 7 antibody (Clone FIB21) specifically detects Integrin beta 7 in FACS. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7672783
发货至: 中国
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Quick Overview for Integrin beta 7 抗体 (APC) (ABIN7672783)

抗原

See all Integrin beta 7 (ITGB7) 抗体
Integrin beta 7 (ITGB7)

适用

  • 74
  • 26
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 52
  • 15
  • 7
  • 4
  • 1
大鼠

克隆类型

  • 53
  • 24
  • 2
单克隆

标记

  • 38
  • 7
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Integrin beta 7 antibody is conjugated to APC

应用范围

  • 40
  • 24
  • 22
  • 13
  • 13
  • 7
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

FIB21
  • 原理

    APC Anti-Human/Mouse Integrin β7 Antibody

    纯化方法

    0

    纯度

    0

    亚型

    IgG2b, kappa
  • 应用备注

    Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    4 °C

    储存方法

    2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Integrin beta 7 (ITGB7)

    别名

    Integrin beta7

    背景

    Synonyms: β7 Integrin|integrin βp|ITGB7

    Background: Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.

    分子量

    0

    基因ID

    3695

    UniProt

    P26010, P26011

    途径

    Integrin Complex
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