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IL-21 抗体 (APC)

This anti-IL-21 antibody is a 小鼠 单克隆 antibody detecting IL-21 in FACS. Suitable for 人.
产品编号 ABIN7672777
发货至: 中国

Quick Overview for IL-21 抗体 (APC) (ABIN7672777)

抗原

See all IL-21 (IL21) 抗体
IL-21 (IL21) (Interleukin 21 (IL21))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-21 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)

克隆位点

3A3-N2
  • 原理

    APC Anti-Human IL-21 Antibody

    纯化方法

    0

    纯度

    0

    亚型

    IgG1, kappa
  • 应用备注

    Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    4 °C

    储存方法

    2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    IL-21 (IL21) (Interleukin 21 (IL21))

    别名

    IL-21

    背景

    Synonyms: IL-21|Interleukin-21|Za11

    Background: Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.

    分子量

    0

    基因ID

    59067

    UniProt

    Q9HBE4

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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