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8-OHDG 抗体

This 兔 多克隆 anti-8-OHDG antibody specifically detects 8-OHDG in IHC 和 IF. The antibody is reactive with not_set samples.
产品编号 ABIN7672607
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for 8-OHDG 抗体 (ABIN7672607)

抗原

8-OHDG (8-Hydroxyguanosine (8-OHDG))

宿主

  • 9
  • 1
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克隆类型

  • 9
  • 2
多克隆

标记

  • 11
This 8-OHDG antibody is un-conjugated

应用范围

  • 8
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
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Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    8-OHDG antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    KLH conjugated 8-OHdG

    亚型

    IgG
  • 应用备注

    IHC: 1:50 - 1:500, IF: 1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.06 % PC300 and 50 % glycerol pH 7.3,

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    8-OHDG (8-Hydroxyguanosine (8-OHDG))

    别名

    8-OHDG

    物质类

    Chemical

    背景

    Synonyms: 8-hydroxy-2'-deoxyguanosine|2'-Deoxy-8-oxoguanosine|7,8-Dihydro-8-oxo-2'-deoxyguanosine|8-Oxo-7,8-dihydro-2'-deoxyguanosine|8-Oxo-7,8-dihydrodeoxyguanosine|2'-Deoxy-8-oxo-D-guanosine|8-Oxo-7,8-dihydro-2μ-deoxyguanosine,8-Oxo-dG|2'-Deoxy-8-hydroxyguanosine

    Background: 8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.

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