8-OHDG 抗体
Quick Overview for 8-OHDG 抗体 (ABIN7672607)
抗原
宿主
克隆类型
标记
应用范围
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原理
- 8-OHDG antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- KLH conjugated 8-OHdG
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亚型
- IgG
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应用备注
- IHC: 1:50 - 1:500, IF: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.06 % PC300 and 50 % glycerol pH 7.3,
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- 8-OHDG (8-Hydroxyguanosine (8-OHDG))
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别名
- 8-OHDG
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物质类
- Chemical
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背景
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Synonyms: 8-hydroxy-2'-deoxyguanosine|2'-Deoxy-8-oxoguanosine|7,8-Dihydro-8-oxo-2'-deoxyguanosine|8-Oxo-7,8-dihydro-2'-deoxyguanosine|8-Oxo-7,8-dihydrodeoxyguanosine|2'-Deoxy-8-oxo-D-guanosine|8-Oxo-7,8-dihydro-2μ-deoxyguanosine,8-Oxo-dG|2'-Deoxy-8-hydroxyguanosine
Background: 8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.
抗原
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