8-OHDG 抗体
(9 references)-
- 抗原 See all 8-OHDG products
- 8-OHDG (8-Hydroxyguanosine (8-OHDG))
- 适用
- 请咨询
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This 8-OHDG antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 交叉反应 （详细）
- 8-OHdG
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated 8-OhdG
- 亚型
- IgG
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anti-8-Hydroxyguanosine (8-OHDG) antibody
8-OHDG ELISA, IHC 宿主: 小鼠 Monoclonal N45-1 unconjugated
anti-8-Hydroxyguanosine (8-OHDG) antibody8-OHDG 适用: 人 ELISA, IHC, IP, FACS, FM 宿主: 小鼠 Monoclonal 15A3 unconjugated
anti-8-Hydroxyguanosine (8-OHDG) antibody8-OHDG IHC (p), EIA, IHC (fro) 宿主: 小鼠 Monoclonal 15A3 unconjugated
anti-8-Hydroxyguanosine (8-OHDG) antibody8-OHDG ELISA, IHC, WB 宿主: 小鼠 Monoclonal 15A3 unconjugated
anti-8-Hydroxyguanosine (8-OHDG) antibody8-OHDG IHC (p), EIA, IF 宿主: 小鼠 Monoclonal N45-1 unconjugated
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- 应用备注
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IHC-P 1:100-500
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "Suppression of neuroinflammation and α-synuclein oligomerization by rotarod walking exercise in subacute MPTP model of Parkinson's disease." in: Neurochemistry international, Vol. 165, pp. 105519, (2023) (PubMed).
: "Antioxidants reduce neurodegeneration and accumulation of pathologic Tau proteins in the auditory system after blast exposure." in: Free radical biology & medicine, Vol. 108, pp. 627-643, (2017) (PubMed).
: "In vitro the differences of inflammatory and oxidative reactions due to sulfur mustard induced acute pulmonary injury underlying intraperitoneal injection and intratracheal instillation in rats." in: International immunopharmacology, Vol. 47, pp. 78-87, (2017) (PubMed).
: "Transcriptomic pathway analysis of urokinase receptor silenced breast cancer cells: a microarray study." in: Oncotarget, Vol. 8, Issue 60, pp. 101572-101590, (2017) (PubMed).
: "Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents Atherosclerosis." in: Circulation research, Vol. 119, Issue 6, pp. e76-90, (2016) (PubMed).
: "Oxidative stress, mitochondrial perturbations and fetal programming of renal disease induced by maternal smoking." in: The international journal of biochemistry & cell biology, Vol. 64, pp. 81-90, (2015) (PubMed).
: "Ameliorative effects of N-acetylcysteine on fluoride-induced oxidative stress and DNA damage in male rats' testis." in: Mutation research. Genetic toxicology and environmental mutagenesis, Vol. 792, pp. 35-45, (2015) (PubMed).
: "Electrochemiluminescence immunosensor for highly sensitive detection of 8-hydroxy-2'-deoxyguanosine based on carbon quantum dot coated Au/SiO2 core-shell nanoparticles." in: Talanta, Vol. 131, pp. 379-85, (2014) (PubMed).
: "Plumbagin ameliorates diabetic nephropathy via interruption of pathways that include NOX4 signalling." in: PLoS ONE, Vol. 8, Issue 8, pp. e73428, (2013) (PubMed).
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: "Suppression of neuroinflammation and α-synuclein oligomerization by rotarod walking exercise in subacute MPTP model of Parkinson's disease." in: Neurochemistry international, Vol. 165, pp. 105519, (2023) (PubMed).
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- 抗原
- 8-OHDG (8-Hydroxyguanosine (8-OHDG))
- Abstract
- 8-OHDG 产品
- 物质类
- Chemical
- 背景
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Synonyms: 8-Hydroxy-2'-deoxyguanosine, 8-Hydroxydeoxyguanosine, 8 hydroxyguanine, 8 hydroxyguanosine, 8 OHG, 8-OHG, 8OG, 8OHdG, 8OHG,
Background: 8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.
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