SAA1 抗体
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北京 101111
Quick Overview for SAA1 抗体 (ABIN7670747)
抗原
See all SAA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Serum Amyloid A1/SAA Monoclonal Antibody(Detector)
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纯化方法
- Protein A/G Purification
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免疫原
- Recombinant Human Serum Amyloid A1/SAA protein expressed by E.coli
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亚型
- IgG2a
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anti-Serum Amyloid A1 (SAA1) (AA 19-122) antibody
SAA1 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1A12E5 unconjugated
anti-Serum Amyloid A1 (SAA1) (AA 1-122) antibodySAA1 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 3C11-2C1 unconjugated
anti-Serum Amyloid A1 (SAA1) (AA 19-212) antibodySAA1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 6A5B10 unconjugated
anti-Serum Amyloid A1 (SAA1) (AA 20-122) antibodySAA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Serum Amyloid A1 (SAA1) antibodySAA1 适用: 人 ELISA, WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Serum Amyloid A1 (SAA1) (AA 1-100) antibodySAA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Serum Amyloid A1 (SAA1) antibodySAA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Serum Amyloid A1 (SAA1) (AA 1-122) antibodySAA1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Serum Amyloid A1 (SAA1) antibodyAnimal-Free SAA1 适用: 人 ELISA 宿主: 小鼠 Monoclonal AB492-2-C08 unconjugated Recombinant Antibody
anti-Serum Amyloid A1 (SAA1) (AA 1-122) antibodySAA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA Detector 0.1-0.4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- SAA1 (Serum Amyloid A1 (SAA1))
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别名
- Serum Amyloid A1/SAA
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背景
- Serum amyLoid A-1 protein,SAA,SAA1,The apolipoproteins are a structurally-unrelated group of proteins that have some association with the transport of lipids in blood. Apolipoproteins,plus phospholipids,cholesterol and triglycerides,form spherical particles with a lipid/hydrophobic center and a (apolipo)protein coat. The apolipoprotein coat promotes aqueous solubility and serves as a ligand for lipoprotein receptors. HDl may contain apolipoproteins A,C,D,E,J,l and M,while lDl contains apolipoproteins B and E. ApoAI and ApoA2 are major protein components of serum high-density lipoprotein (HDl) and are produced by the liver and small intestine. They are involved in reverse cholesterol transport from tissues to the liver. Polymorphisms of ApoA2 are associated with disorders of cholesterol and fatty acid metabolism. Human ApoB (Apolipoprotein B-100) is a 550 kDa,secreted,palmitoylated glycoprotein that is part of lDl and VlDl particles. It is made by liver and is 4536 aa in length. It binds lDl to the ApoB/E receptor. ApoC activates lipoprotein lipase and may self-associate to form amyloid-type fibrils. ApoE is a 34 kDa protein component of serum chylomicrons,VlDl,and HDl particles. It mediates the binding,uptake,and catabolism of these particles through interactions with the ApoE receptor and lDl receptors in the liver and brain. ApoE is important in fatty acid homeostasis and memory formation. Polymorphisms encode three variants (ApoE2,3,4) which are differentially related to the development of atherosclerosis and neurogenerative disorders,particularly Alzheimer's disease. Serum amyloid A proteins (SAAs) are a family of homologous apolipoproteins of high density lipoprotein (HDl). They can be divided into two groups. The first group consists of the acute phase SAA1 and SAA2 that associate with HDl during inflammation and remodel the HDl particle by displacing apolipoprotein A1. The second group consists of constitutively expressed SAA4 and SAA5 that exist as minor apolipoproteins on HDl but make up more than 90 % of the total SAA during homeostasis.
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UniProt
- P0DJI8
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途径
- Toll-Like Receptors Cascades
抗原
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