PLAUR 抗体
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北京 101111
Quick Overview for PLAUR 抗体 (ABIN7670722)
抗原
See all PLAUR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- uPAR Monoclonal Antibody(Capture)
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纯化方法
- Protein A/G Purification
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免疫原
- Recombinant Human uPAR protein expressed by Mammalian
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亚型
- IgG1
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应用备注
- ELISA Capture 2-8 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
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别名
- uPAR
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背景
- CD87,U-PAR,URKR,This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
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UniProt
- Q03405
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途径
- Inositol Metabolic Process
抗原
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