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PLAU 抗体

This anti-PLAU antibody is a 大鼠 单克隆 antibody detecting PLAU in ELISA (Detection). Suitable for 人.
产品编号 ABIN7670721
发货至: 中国

Quick Overview for PLAU 抗体 (ABIN7670721)

抗原

See all PLAU 抗体
PLAU (Plasminogen Activator, Urokinase (PLAU))

适用

  • 86
  • 26
  • 21
  • 5
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  • 4
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  • 1
  • 1
  • 1

宿主

  • 80
  • 17
  • 12
  • 5
  • 1
  • 1
  • 1
大鼠

克隆类型

  • 85
  • 28
  • 2
单克隆

标记

  • 69
  • 15
  • 10
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This PLAU antibody is un-conjugated

应用范围

  • 79
  • 55
  • 42
  • 19
  • 18
  • 16
  • 12
  • 11
  • 10
  • 9
  • 6
  • 3
  • 2
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  • 1
  • 1
ELISA (Detection)

克隆位点

9B8
  • 原理

    Plasminogen Activator/Urokinase Monoclonal Antibody(Detector)

    纯化方法

    Protein A/G Purification

    免疫原

    Recombinant Human Plasminogen Activator/Urokinase protein expressed by Mammalian

    亚型

    IgG1
  • 应用备注

    ELISA Detector 0.1-0.4 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Sterile PBS , pH 7.4

    储存液

    Without preservative

    注意事项

    Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C Valid for 1 month or -20°C Valid for 12 months

    有效期

    12 months
  • 抗原

    PLAU (Plasminogen Activator, Urokinase (PLAU))

    别名

    Plasminogen Activator/Urokinase

    背景

    UPA,u-PA,ATF,URK,UP-A,Urokinase,Abbokinase,This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    UniProt

    P00749

    途径

    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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