HMOX1 抗体
Quick Overview for HMOX1 抗体 (ABIN7670621)
抗原
See all HMOX1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- HO1/HMOX1 Polyclonal Antibody
-
纯化方法
- Antigen Affinity Purification
-
免疫原
- Recombinant Human HO1/HMOX1 protein expressed by E.coli
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-1:1000,IHC 1:500-1:1000,ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- Sterile PBS , pH 7.4
-
储存液
- Without preservative
-
注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
-
有效期
- 12 months
-
-
- HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))
-
别名
- HO1/HMOX1
-
背景
- Heme oxygenase 1,HO-1,HMOX1,HO,HO1,EC:1.14.14.18,Heme Oxygenase (HO),also known as HMOX,is the rate limiting enzyme in the breakdown of heme into Biliverdin,CO,and iron. There are two major isoforms of this enzyme,HO-1 and HO-2. Both have similar enzymatic activity,however,HO-1 is rapidly inducible,while HO-2 is constitutively expressed. Inducers of HO-1 include cell stressors such as oxidative stress,infection,hypoxia,and cytotoxic agents. The reaction products generated by HO-1 activity are biologically active,and the enzyme has a broad range of putative roles. For instance,Biliverdin is an antioxidant with cytoprotective and anti-inflammatory properties,and CO has the potential to suppress inflammation and apoptosis. Because of these activities,HO-1 has received much attention as a therapeutic target for a range of pathological processes.
-
分子量
-
Calculated MW: 33kDa
ObservedMW: 25kDa
-
UniProt
- P09601
-
途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
抗原
-