Granulin 抗体
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北京 101111
Quick Overview for Granulin 抗体 (ABIN7670620)
抗原
See all Granulin (GRN) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Progranulin/PGRN Polyclonal Antibody(Capture/Detector)
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纯化方法
- Antigen Affinity Purification
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免疫原
- Recombinant Human Progranulin/PGRN protein expressed by Mammalian
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亚型
- IgG
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应用备注
- ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- Granulin (GRN)
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别名
- Progranulin/PGRN
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背景
- Proepithelin,PC cell-derived growth factor,Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.
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UniProt
- P28799
抗原
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