Endoglin 抗体
Quick Overview for Endoglin 抗体 (ABIN7670592)
抗原
See all Endoglin (ENG) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Endoglin/CD105 Polyclonal Antibody(Capture/Detector)
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纯化方法
- Antigen Affinity Purification
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免疫原
- Recombinant Human Endoglin/CD105 protein expressed by E.coli
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亚型
- IgG
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应用备注
- ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- Endoglin (ENG)
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别名
- Endoglin/CD105
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背景
- ENG,CD105,EndogLin,END,Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis.Required for normal structure and integrity of adult vasculature.Regulates the migration of vascular endothelial cells.Required for normal extraembryonic angiogenesis and for embryonic heart development.May regulate endothelial cell shape changes in response to blood flow,which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors.Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3.
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UniProt
- P17813
抗原
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