M-CSF/CSF1 抗体
Quick Overview for M-CSF/CSF1 抗体 (ABIN7670577)
抗原
See all M-CSF/CSF1 (CSF1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- M-CSF Polyclonal Antibody(Capture/Detector)
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纯化方法
- Antigen Affinity Purification
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免疫原
- Recombinant Human M-CSF protein expressed by E.coli
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亚型
- IgG
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anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-204) antibody
CSF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) antibodyCSF1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 201-300) antibodyCSF1 适用: 人, 小鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (Middle Region) antibodyCSF1 适用: 人, 小鼠, 大鼠, 犬, Pig, 豚鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-132) antibodyCSF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A9 unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 261-427) antibodyCSF1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 230-257) antibodyCSF1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB18764 unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (C-Term) antibodyCSF1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-554) antibodyCSF1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) antibody (Biotin)CSF1 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
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应用备注
- ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
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别名
- M-CSF
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背景
- M-CSF,CSF1,CSF-1,Macrophage colony-stimulating factor 1,also known as CSF-1,M-CSF,Lanimostim and CSF1,is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production,differentiation,and function of 2 related white cell populations of the blood,the granulocytes and the monocytes-macrophages. M-CSF/CSF-1 is known to facilitate monocyte survival,monocyte-to-macrophage conversion,and macrophage proliferation. M-CSF/CSF-1 is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. It binds to the Colony stimulating factor 1 receptor. M-CSF/CSF-1 may also be involved in development of the placenta. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer,and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses,bone metabolism,lipoproteins clearance,fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage,but also by regulating endothelial cell chemokine expression.
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UniProt
- P09603
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途径
- RTK signaling
抗原
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