ACE2 抗体
Quick Overview for ACE2 抗体 (ABIN7670534)
抗原
See all ACE2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- ACE2 Monoclonal Antibody(Detector)
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纯化方法
- Protein A/G Purification
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免疫原
- Recombinant Human ACE2 protein expressed by Mammalian
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亚型
- IgG2a
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anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 601-700) antibody
ACE2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 18-250) antibodyACE2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) antibodyACE2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal AC18F unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 93-464) antibodyACE2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 392-739) antibodyACE2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (N-Term) antibodyVerified ACE2 适用: 人 WB, IHC, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 773-805), (C-Term) antibodyACE2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4819 unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 140-172) antibodyACE2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 59-90) antibodyACE2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiotensin I Converting Enzyme 2 (ACE2) (AA 351-450) antibodyACE2 适用: 人, 小鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA Detector 0.1-0.4 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Sterile PBS , pH 7.4
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储存液
- Without preservative
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注意事项
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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有效期
- 12 months
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- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
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别名
- ACE2
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背景
- ACEH,ACEII,ACE2 (Angiotensin-converting enzyme 2),also named as ACEH,is a zinc metalloprotease of the ACE family and a critical regulator of the reninangiotensin system. ACE2 has a more restricted tissue distribution than ACE,being found predominantly in the heart,kidneys,and testes although low levels have been detected in a variety of tissues. ACE2 has been shown to be a functional receptor of the human coronaviruses SARS-CoV and SARS-CoV-2. The expression level and expression pattern of human ACE2 in different tissues might be critical for the susceptibility,symptoms,and outcome of 2019-nCoV/SARS-CoV-2 infection. It can be used as a potential therapeutic target of SARS-CoV-2. The calculated molecular weight of ACE2 is 92 kDa but it migrates to 120 kDa due to N-glycosylation . Sometimes,several cleaved fragments can also be detected as 75 kDa,50 kDa or 37 kDa. It has 2 isoforms produced by alternative splicing. This antibody is specific to ACE2. The location of ACE2 is membrane and cytoplasm,however it accumulates in the nucleus during the mitosis.
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UniProt
- Q9BYF1
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途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
抗原
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