MCAM 抗体 (PE)
Quick Overview for MCAM 抗体 (PE) (ABIN7670248)
抗原
See all MCAM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PE Anti-Mouse CD146 Antibody[ME-9F1]
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免疫原
- E-AB-F09832D
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亚型
- IgG2a, kappa
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anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 84-189) antibody
MCAM 适用: 人 FACS, IHC, WB, ELISA 宿主: 小鼠 Monoclonal 6C3E6 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 50-646) antibodyMCAM 适用: 人 FACS, WB, IF, ELISA 宿主: 小鼠 Monoclonal 4D10C7 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 447-646) antibodyMCAM 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyMCAM 适用: 人 FACS, IHC, WB, IF, ELISA 宿主: 兔 Monoclonal 8A10 unconjugated Recombinant Antibody
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyMCAM 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 1-646) antibodyMCAM 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 226-374) antibodyMCAM 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal MCAM-3046 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 201-300) antibodyMCAM 适用: 人, 大鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyMCAM 适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 24-646) antibodyMCAM 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 3H6 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 5 μL/tests
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant
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注意事项
- Please protected from prolonged exposure to light and do not freeze.
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储存条件
- 4 °C
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储存方法
- This product can be stored at 2-8°C for 12 months.
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有效期
- 12 months
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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别名
- CD146
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背景
- S-Endo 1 antigen,MUC18,MCAM,Mel-CAM,A32 antigen,CD146, also known as melanoma cell adhesion molecule (MCAM or Mel-CAM), MUC18, S-Endo1, and A32 antigen, is an integral membrane glycoprotein that belongs to the Ig superfamily. CD146 is strongly expressed by murine vascular endothelial cells. It is expressed on about 30 % of neutrophils and 60 % of NK cells. Unlike in humans, CD146 is undetectable on monocytes, dendritic cells, T cells, NKT cells, B cells, or smooth muscle cells in mouse. It has been reported that an increase in CD146 expression is associated with NK cell maturation. Combined with using CD27 and CD11b staining, CD146 may be an alternative marker to detect final stages of NK cell maturation and define NK cell subsets. CD146+ NK cells were found to be less cytotoxic and to produce less IFNγ than CD146- NK cells upon stimulation with target cells or activating antibodies. The role of CD146 on NK cell migration has yet to be investigated. The identification of CD146 ligand(s) will be crucial to address this issue.
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UniProt
- P10810
抗原
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