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Integrin beta 7 抗体 (PE)

This 大鼠 单克隆 antibody specifically detects Integrin beta 7 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7670235
发货至: 中国
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Quick Overview for Integrin beta 7 抗体 (PE) (ABIN7670235)

抗原

See all Integrin beta 7 (ITGB7) 抗体
Integrin beta 7 (ITGB7)

适用

  • 73
  • 26
  • 1
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宿主

  • 52
  • 14
  • 7
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  • 1
大鼠

克隆类型

  • 53
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  • 2
单克隆

标记

  • 38
  • 7
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Integrin beta 7 antibody is conjugated to PE

应用范围

  • 40
  • 23
  • 22
  • 13
  • 13
  • 7
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Flow Cytometry (FACS)

克隆位点

FIB504
  • 原理

    PE Anti-Human Integrin β7 Antibody[FIB504]

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    5 μL/tests

    缓冲液

    Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

    注意事项

    Please protected from prolonged exposure to light and do not freeze.

    储存条件

    4 °C

    储存方法

    This product can be stored at 2-8°C for 12 months.

    有效期

    12 months
  • 抗原

    Integrin beta 7 (ITGB7)

    别名

    Integrin beta7

    背景

    CEACAM1a,Bgp,Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.

    UniProt

    P31809

    途径

    Integrin Complex
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