CD8 抗体 (FITC)
Quick Overview for CD8 抗体 (FITC) (ABIN7670214)
抗原
See all CD8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- FITC Anti-Human CD8 Antibody[SK1]
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免疫原
- E-AB-F09792C
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 5 μL/tests
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
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注意事项
- Please protected from prolonged exposure to light and do not freeze.
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储存条件
- 4 °C
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储存方法
- This product can be stored at 2-8°C for 12 months.
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有效期
- 12 months
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- CD8
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别名
- CD8
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背景
- T8,Leu2,CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck
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UniProt
- P01732
抗原
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