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PD-L1 抗体 (FITC)

This 小鼠 单克隆 antibody specifically detects PD-L1 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7670211
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for PD-L1 抗体 (FITC) (ABIN7670211)

抗原

See all PD-L1 抗体
PD-L1 (CD274 (PD-L1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PD-L1 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

9F7
  • 原理

    FITC Anti-Human CD274/PD-L1 Antibody[9F7]

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    5 μL/tests

    缓冲液

    Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

    注意事项

    Please protected from prolonged exposure to light and do not freeze.

    储存条件

    4 °C

    储存方法

    This product can be stored at 2-8°C for 12 months.

    有效期

    12 months
  • 抗原

    PD-L1 (CD274 (PD-L1))

    别名

    CD274

    背景

    B7-H1,PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H,B7H1,PDL1,PDCD1L1,PDCD1LG1,CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.

    UniProt

    Q9NZQ7

    途径

    Cancer Immune Checkpoints
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