CD80 抗体
Quick Overview for CD80 抗体 (ABIN7670164)
抗原
See all CD80 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- AF/LE Purified Anti-Human CD80 Antibody[2D10]
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内毒素水平
- Low Endotoxin
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- ≥ 1 mg/mL
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缓冲液
- Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.
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储存液
- Azide free
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注意事项
- avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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有效期
- 12 months
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- CD80
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别名
- CD80
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背景
- LAB,CTLA-4 counter-receptor B,T-lymphocyte activation antigen CD,B7,B7-1,B7.1,BB1,CD28LG,CD28LG1,LAB7,CD80,CD28LGB7-1 antigen,T-lymphocyte activation antigen CD80,Activation B7-1 antigen,CTLA-4 counter-receptor B7.1, B7-1, BB1,B lymphocyte activation antigen B7,B7-1 antigen,B7-1 antigen),CD28 antigen ligand 1,CD80 antigen,CD80 antigen (CD28 antigen ligand 1,CD80 Molecule,Costimulatory factor CD80,costimulatory molecule variant IgV-CD80,B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages.
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UniProt
- P33681
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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