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FLT3 抗体

This 小鼠 单克隆 antibody specifically detects FLT3 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN7670058
发货至: 中国
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Quick Overview for FLT3 抗体 (ABIN7670058)

抗原

See all FLT3 抗体
FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This FLT3 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

BV10(BV10A4)
  • 原理

    Purified Anti-Human CD135 Antibody[BV10(BV10A4)]

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    ≥ 1 mg/mL

    缓冲液

    Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    avoid freeze / thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

    别名

    CD135

    背景

    Fetal Liver Kinase,Fms-Like Tyrosine Kinase,Stem Cell Tyrosine Kinase,Receptor-Type Tyrosine-Protein Kinase FLT,FLT,FLK,STK,FLT3,CD135,FLK-2,FLK2,STK1,Fetal Liver Kinase-2,FL Cytokine Receptor,FLT-3,Fms-Like Tyrosine Kinase 3,Receptor-Type Tyrosine-Protein Kinase FLT3,Stem Cell Tyrosine Kinase 1,STK-1,Flt3/Flk2, STK-1,CD 135,CD135 antigen,Fetal liver kinase 2,Flk 2,Flt 3,FMS like tyrosine kinase 3,Fms related tyrosine kinase 3,Fms-Related Tyrosine Kinase 3,Growth factor receptor tyrosine kinase type III,Ly-72,OTTHUMP0000004234,Receptor type tyrosine protein kinase FLT3,Stk 1,Tyrosine protein kinase receptor FLT3,Tyrosine-protein kinase receptor FLT3,This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

    UniProt

    P36888

    途径

    RTK signaling
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