CD276 抗体
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北京 101111
Quick Overview for CD276 抗体 (ABIN7670004)
抗原
See all CD276 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Purified Anti-Human CD276 Antibody[6A1]
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- ≥ 1 mg/mL
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- avoid freeze / thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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有效期
- 12 months
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- CD276
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别名
- CD276
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背景
- B7H;UNQ;PRO;B7-H;B7RP;B7 homolog;B7H34Ig-B7-H;PSEC;4Ig-B7-H;CD276;4Ig-B7-H3;B7-H3;B7H3;B7RP-2;B7 homolog 3;B7H34Ig-B7-H3;CD276 antigen;CD276 molecule;Costimulatory molecule;PSEC0249;UNQ309;PRO352; B7RP-2;4Ig-B7-H3;B7H3;B7-H3;CD276 antigen,The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q5ZPR3
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途径
- Cancer Immune Checkpoints
抗原
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