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Recombinant VLDLR 抗体 (C-Term) (CF®488A)

This anti-VLDLR antibody is a 兔 单克隆 antibody detecting VLDLR in . Suitable for 人 和 大鼠.
产品编号 ABIN7661872
发货至: 中国

Quick Overview for Recombinant VLDLR 抗体 (C-Term) (CF®488A) (ABIN7661872)

抗原

See all VLDLR 抗体
VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

抗体类型

Recombinant Antibody

适用

  • 80
  • 34
  • 26
  • 6
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  • 3
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  • 3
人, 大鼠

宿主

  • 65
  • 18

克隆类型

  • 54
  • 29
单克隆

标记

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  • 6
  • 4
  • 4
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  • 2
  • 2
  • 2
  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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This VLDLR antibody is conjugated to CF®488A

应用范围

请咨询

克隆位点

VLDLR-2896R
  • 抗原表位

    • 27
    • 16
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    VLDL-Receptor (Very Low Density Lipoprotein Receptor)(VLDLR/2896R), CF488A conjugate

    产品特性

    VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human VLDLR fragment from c-terminal

    亚型

    IgG
  • 应用备注

    For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

    说明

    Positive Control: HeLa or U-251 cells. Pancreas, Cerebellum, Heart or Skeletal Muscle.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

    别名

    VLDL Receptor

    背景

    Synonyms: Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR

    Gene Symbol: VLDLR

    分子量

    143-161 kDa

    基因ID

    7436

    UniProt

    P98155

    途径

    Cellular Response to Molecule of Bacterial Origin
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