UACA 抗体 (CF®740)
Quick Overview for UACA 抗体 (CF®740) (ABIN7661694)
抗原
See all UACA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- UACA / Nucling(AE-5), CF740 conjugate
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产品特性
- UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Nuclei of myeloid leukemia biopsy cells
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亚型
- IgG1, kappa
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anti-Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) (AA 29-209) antibody
UACA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) (AA 1-90) antibodyUACA 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) antibodyUACA 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) (AA 1-1416) antibodyUACA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) antibodyUACA 适用: 人, 小鼠 WB, IF, FACS 宿主: 小鼠 Monoclonal AE-5 unconjugated
anti-Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) (AA 1309-1358) antibodyUACA 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Immunofluorescence 0.5-1.0 μg/mL. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: HeLa or 293T cells. Highly expressed in skeletal muscle, heart, kidney and pancreas. Also expressed in epidermal melanocytes, eye muscles and thyroid follicular cells.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))
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别名
- Nucling
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背景
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Synonyms: Nuclear membrane binding protein, Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA), NUCLING
Gene Symbol: UACA
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分子量
- 160 kDa
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基因ID
- 55075
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UniProt
- Q9BZF9
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途径
- Positive Regulation of Endopeptidase Activity
抗原
-
