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Uroplakin 1B 抗体 (AA 109-229) (CF®568)

This anti-Uroplakin 1B antibody is a 小鼠 单克隆 antibody detecting Uroplakin 1B in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7661672
发货至: 中国

Quick Overview for Uroplakin 1B 抗体 (AA 109-229) (CF®568) (ABIN7661672)

抗原

See all Uroplakin 1B (UPK1B) 抗体
Uroplakin 1B (UPK1B)

适用

  • 53
  • 4
  • 3

宿主

  • 35
  • 18
小鼠

克隆类型

  • 35
  • 18
单克隆

标记

  • 23
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
This Uroplakin 1B antibody is conjugated to CF®568

应用范围

  • 37
  • 29
  • 18
  • 17
  • 7
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

UPK1B-3081
  • 抗原表位

    • 34
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 109-229

    原理

    Uroplakin 1B (Urothelial Differentiation Marker)(UPK1B/3081), CF568 conjugate

    产品特性

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. UPK1B is expressed by terminally differentiated urothelial cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant fragment (around aa 109-229) of human Uroplakin 1B (UPK1B) protein

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Urinary Bladder.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Uroplakin 1B (UPK1B)

    别名

    Uroplakin 1B

    背景

    Synonyms: Tetraspanin-20, Tspan-20, TSPAN20, UP1b, UPIb, UPK1B, Uroplakin-1b

    Gene Symbol: UPK1B

    分子量

    ~30 kDa

    基因ID

    7348

    UniProt

    O75841
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