TACSTD2 抗体 (AA 31-274) (CF®405S)
Quick Overview for TACSTD2 抗体 (AA 31-274) (CF®405S) (ABIN7661431)
抗原
See all TACSTD2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 31-274
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原理
- TACSTD2 / TROP2 (Epithelial Marker) (TACSTD2/2152), CF405S conjugate
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产品特性
- TACSTD2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment of human TACSTD2 protein (around aa 31-274)
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亚型
- IgG1, kappa
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Western blotting 0.5-1 μg/mL. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: HT29 cells. Breast or Colon Carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))
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别名
- TACSTD2
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背景
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Synonyms: Cell surface glycoprotein Trop-2, Membrane Component Chromosome 1, Surface Marker 1 (M1S1), Pancreatic Carcinoma Marker Protein GA733-1, TROP2, Tumor-Associated Calcium Signal Transducer 2 (TACSTD2)
Gene Symbol: TACSTD2
Tissue Expression: Cornea|Epithelial cells|Placenta
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分子量
- 40 kDa
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基因ID
- 4070
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UniProt
- P09758
抗原
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