TCF4 抗体 (AA 365-671) (CF®740)
Quick Overview for TCF4 抗体 (AA 365-671) (CF®740) (ABIN7660958)
抗原
See all TCF4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 365-671
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原理
- TCF4 (Transcription Factor 4) (TCF4/1705), CF740 conjugate
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产品特性
- This antibody recognizes a protein of 71 kDa, identified as Transcription Factor 4 (TCF4). It is a basic helix-loop-helix transcription factor. The protein recognizes an Ephrussi-box (E-box) binding site (CANNTG) - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human TCF4 protein fragment (around aa 365-671)
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亚型
- IgG2a, kappa
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应用备注
- ELISA: Use Ab at 2-4 μg/mL for coating, Order Ab without BSA, Western blot 1-2 μg/mL, Optimal dilution for a specific application should be determined.. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
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说明
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Positive Control: HeLa or HepG2 cells. Bladder
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- TCF4 (Transcription Factor 4 (TCF4))
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别名
- TCF4
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背景
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Synonyms: bHLHb19, Class B basic helix-loop-helix protein 19, Immunoglobulin transcription factor 2, ITF-2, PTHS, SEF2, SL3-3 enhancer factor 2, TCF4, Transcription factor 4
Gene Symbol: TCF4
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分子量
- 71 kDa
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基因ID
- 6925
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UniProt
- P15884
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途径
- WNT signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus
抗原
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