TSHB 抗体 (Biotin)
Quick Overview for TSHB 抗体 (Biotin) (ABIN7660829)
抗原
See all TSHB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker)(TSHb/1317), Biotin conjugate
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产品特性
- The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH) follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human TSH beta fragment
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亚型
- IgG1, kappa
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anti-Thyroid Stimulating Hormone, beta (TSHB) (AA 20-139) antibody
TSHB 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1D12G1 unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) antibodyTSHB 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) antibodyTSHB 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) (AA 21-138) antibodyTSHB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) (AA 58-86) antibodyTSHB 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21119 unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) (AA 21-138) antibodyTSHB 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) (AA 20-138) antibodyTSHB 适用: 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) antibodyTSHB 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal TSHb-1317 unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) (AA 51-138) antibodyTSHB 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 小鼠 Polyclonal unconjugated
anti-Thyroid Stimulating Hormone, beta (TSHB) antibodyTSHB 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Normal pituitary or its tumor.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- TSHB (Thyroid Stimulating Hormone, beta (TSHB))
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别名
- Thyroid Stimulating Hormone, beta
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背景
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Synonyms: CHNG4, Thyroid stimulating hormone beta subunit, Thyroid stimulating hormone, beta precursor, Thyrotropin beta subunit, TSHB
Gene Symbol: TSHB
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分子量
- 16 kDa
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基因ID
- 7252
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UniProt
- P01222
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途径
- Thyroid Hormone Synthesis, Peptide Hormone Metabolism
抗原
-
