TCP1 alpha/CCTA 抗体 (Biotin)
Quick Overview for TCP1 alpha/CCTA 抗体 (Biotin) (ABIN7660627)
抗原
See all TCP1 alpha/CCTA (TCP1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- p63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/2428), Biotin conjugate
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产品特性
- p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human p63 protein
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亚型
- IgG2b, kappa
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anti-T-Complex 1 (TCP1) (AA 1-556) antibody
TCP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2B2-D6 unconjugated
anti-T-Complex 1 (TCP1) (C-Term) antibodyVerified TCP1 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-T-Complex 1 (TCP1) (AA 82-98) antibodyTCP1 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-T-Complex 1 (TCP1) (AA 406-506) antibodyTCP1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-T-Complex 1 (TCP1) (C-Term) antibodyTCP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-T-Complex 1 (TCP1) (AA 307-556) antibodyTCP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Complex 1 (TCP1) (AA 600-680) antibodyTCP1 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-063R unconjugated Recombinant Antibody
anti-T-Complex 1 (TCP1) (C-Term) antibodyTCP1 适用: 小鼠 WB, IF, FACS, IP, ICC 宿主: 大鼠 Monoclonal 91a unconjugated
anti-T-Complex 1 (TCP1) (C-Term) antibody (HRP)TCP1 适用: 小鼠 WB, IF, FACS, IP, ICC 宿主: 大鼠 Monoclonal 91a HRP
anti-T-Complex 1 (TCP1) (C-Term) antibody (FITC)TCP1 适用: 小鼠 WB, IF, FACS, IP, ICC 宿主: 大鼠 Monoclonal 91a FITC
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: HEK293 cells or Prostate Carcinoma or Lung or bladder squamous cell carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
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别名
- p63
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背景
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Synonyms: Amplified in squamous cell carcinoma (AIS), Chronic ulcerative stomatitis protein (CUSP), EEC3, Keratinocyte transcription factor KET, LMS, NBP, p40, P51/P63, p53 like transcription factor, p53-related protein p63, RHS, SHFM4, TAp63alpha, TP53CP, TP53L, TP63, TP73, TP73L, Transformation-related protein 63, Trp53rp1, Trp6,3, Tumor protein 63, Tumor protein p53-like, tumor protein p73-like
Gene Symbol: TP63
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分子量
- 63 kDa
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基因ID
- 8626
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UniProt
- Q9H3D4
抗原
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