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TCP1 alpha/CCTA 抗体 (CF®405S)

This anti-TCP1 alpha/CCTA antibody is a 兔 单克隆 antibody detecting TCP1 alpha/CCTA in IHC 和 IHC (fp). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7660595
发货至: 中国

Quick Overview for TCP1 alpha/CCTA 抗体 (CF®405S) (ABIN7660595)

抗原

See all TCP1 alpha/CCTA (TCP1) 抗体
TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This TCP1 alpha/CCTA antibody is conjugated to CF®405S

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

TP63-1423R
  • 原理

    p63 (Squamous, Basal & Myoepithelial Cell Marker)(TP63/1423R), CF405S conjugate

    产品特性

    p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human p63 protein fragment

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: HEK293 cells. Prostate Carcinoma or Lung or bladder squamous cell carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

    别名

    p63

    背景

    Synonyms: Amplified in squamous cell carcinoma (AIS), Chronic ulcerative stomatitis protein (CUSP), EEC3, Keratinocyte transcription factor KET, LMS, NBP, p40, P51/P63, p53 like transcription factor, p53-related protein p63, RHS, SHFM4, TAp63alpha, TP53CP, TP53L, TP63, TP73, TP73L, Transformation-related protein 63, Trp53rp1, Trp6, 3, Tumor protein 63, Tumor protein p53-like, tumor protein p73-like

    Gene Symbol: TP63

    分子量

    63 kDa

    基因ID

    8626

    UniProt

    Q9H3D4
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