CD1c 抗体 (CF®488A)
Quick Overview for CD1c 抗体 (CF®488A) (ABIN7660589)
抗原
See all CD1c (CD1C) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD1c(CD1C/1603), CF488A conjugate
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产品特性
- The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with -2-Microglobulin and expressed on cortical thymocytes, Langerhans cells, a B cell subset and some dendritic cells. Specifically, CD1A is a marker for Langerhans cell histiocytosis (LCH) and is found on interdigitating cells. Adaptor-protein complexes and CD1-associated chaperones control CD1 trafficking, and the development and activation of CD1-restricted T cells. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. The human CD1 genes are all closely linked in a cluster mapping at chromosome 1q23. 1Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human CD1c protein
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亚型
- IgG1, kappa
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anti-T-cell surface glycoprotein CD1c (CD1C) (AA 18-302) antibody
CD1C 适用: 人 ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 3G1B3 unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibodyCD1C 适用: 人 FACS, IHC, IP 宿主: 小鼠 Monoclonal L161 unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibodyCD1C 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1H9 unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibody (APC)CD1C 适用: 人 FACS 宿主: 小鼠 Monoclonal L161 APC
anti-T-cell surface glycoprotein CD1c (CD1C) (AA 18-300) antibodyCD1C 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibodyCD1C 适用: 人 ELISA, LMNX 宿主: 小鼠 Monoclonal OTI1F4 unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) (AA 18-302) antibodyCD1C 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibodyCD1C 适用: 人, 小鼠, 大鼠, 犬, 猴 WB 宿主: 小鼠 Monoclonal 1E10 unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibody (PE)CD1C 适用: 人 FACS 宿主: 小鼠 Monoclonal L161 PE
anti-T-cell surface glycoprotein CD1c (CD1C) (AA 226-253) antibodyCD1C 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: Expressed on cortical thymocytes, on certain T-cell leukemias and in various other tissues.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))
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别名
- CD1c
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背景
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Synonyms: BDCA1, CD1, CD1A, CD1c, CD1C antigen c polypeptide, CD1c molecule, Cortical thymocyte antigen CD1C, Differentiation antigen CD1 alpha 3, R7, T cell surface glycoprotein CD1c
Gene Symbol: CD1C
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分子量
- 43 kDa
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基因ID
- 911
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UniProt
- P29017
抗原
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