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SHBG 抗体 (CF®740)

This anti-SHBG antibody is a 小鼠 单克隆 antibody detecting SHBG in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7659881
发货至: 中国

Quick Overview for SHBG 抗体 (CF®740) (ABIN7659881)

抗原

See all SHBG 抗体
SHBG (Sex Hormone Binding Globulin (SHBG))

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宿主

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小鼠

克隆类型

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单克隆

标记

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This SHBG antibody is conjugated to CF®740

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

SHBG-245
  • 原理

    SHBG (Sex Hormone Binding Globulin)(SHBG/245), CF740 conjugate

    产品特性

    Recognizes a protein of 45 kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human SHBG protein

    亚型

    IgG1
  • 应用备注

    Immunohistology formalin-fixed 1-2 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes. Immunofluorescence 0.5-1 μg/mL. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: Liver, Placenta or Testis

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % rBSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    SHBG (Sex Hormone Binding Globulin (SHBG))

    别名

    SHBG

    背景

    Synonyms: Androgen binding protein (ABP), Sex hormone-binding globulin (SHBG), Sex steroid binding protein (SBP), Sex steroid-binding protein, Testis-specific androgen-binding protein, Testosterone binding beta globulin, Testosterone-Estradiol-Binding Globulin (TEBG)

    Gene Symbol: SHBG

    Tissue Expression: Testis

    分子量

    45 kDa

    基因ID

    6462

    UniProt

    P04278

    途径

    Hormone Transport
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