SERBP1 抗体 (AA 3-139) (CF®740)
Quick Overview for SERBP1 抗体 (AA 3-139) (CF®740) (ABIN7659826)
抗原
See all SERBP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 3-139
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原理
- PAI-RBP1 / SERBP1 / SERPINE1(SERBP1/3493), CF740 conjugate
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产品特性
- PAI-RBP1 (plasminogen activator inhibitor 1 RNA-binding protein), also known as SERBP1 (SERPINE1 mRNA-binding protein 1), CGI-55, CHD3IP (chromodomain helicase DNA binding protein 3 interacting protein), HABP4L or PAI-RBP1, is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. PAI-RBP1 is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, PAI-RBP1 interacts with Mi2- and may be involved in chromatin remodeling. PAI-RBP1 also interacts with PGRMC1 and participates in the transduction of Progesterone's antiapoptotic action in ovarian cell types. The gene encoding PAI-RBP1 is overexpressed in ovarian cancer, suggesting a possible role for PAI-RBP1 in tumorigenesis and tumor metastasis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment of human SERBP1 protein (around aa3-139)
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亚型
- IgG2b, kappa
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anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-402) antibody
SERBP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1D2-2E9 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-262) antibodySERBP1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5G2 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-262) antibodySERBP1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2E11 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 3-139) antibodySERBP1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal SERBP1-3491 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 3-139) antibodySERBP1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal SERBP1-3493 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 3-139) antibodySERBP1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal SERBP1-3496 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-262) antibodySERBP1 适用: 人, 大鼠, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4F8 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-402) antibodySERBP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G5-2D7 unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 1-408) antibodySERBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SERPINE1 mRNA Binding Protein 1 (SERBP1) (AA 311-360) antibodySERBP1 适用: 人, 小鼠, 大鼠, 犬, 猴, Cow, 豚鼠, 马, 兔, Pig, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: Human kidney or bladder tissue (IHC).
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % rBSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- SERBP1 (SERPINE1 mRNA Binding Protein 1 (SERBP1))
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别名
- PAI-RBP1
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背景
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Synonyms: CGI 55, CHD3IP, Chromodomain helicase DNA binding protein 3 interacting protein, HABP4L, PAI1 RNA-binding protein 1, PAIRBP1, Plasminogen activator inhibitor 1 RNA binding protein, SERPINE1 mRNA binding protein 1
Gene Symbol: SERBP1
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分子量
- 60 kDa
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基因ID
- 26135
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UniProt
- Q8NC51
抗原
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