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RPSA/Laminin Receptor 抗体 (CF®488A)

This anti-RPSA/Laminin Receptor antibody is a 小鼠 单克隆 antibody detecting RPSA/Laminin Receptor in IF 和 FACS. Suitable for 人.
产品编号 ABIN7659646
发货至: 中国

Quick Overview for RPSA/Laminin Receptor 抗体 (CF®488A) (ABIN7659646)

抗原

See all RPSA/Laminin Receptor (RPSA) 抗体
RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This RPSA/Laminin Receptor antibody is conjugated to CF®488A

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

RPSA-2699
  • 原理

    Laminin Receptor / RPSA (Marker of Metastatic Potential)(RPSA/2699), CF488A conjugate

    产品特性

    Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant full-length human RPSA protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: MCF-7, MDA-MB-453, SK-BR3, THP1, HL60, HeLa or HEK293 cells. Breast, Colon or Ovarian Carcinoma, Tonsil.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

    别名

    Laminin Receptor

    背景

    Synonyms: 34/67 kDa Laminin Receptor, 37 kDa Laminin Receptor precursor, 37/67 kDa Laminin Receptor, 37LRP, 40S Ribosomal Protein SA, 67 kDa Laminin Receptor, 67LR, Colon Carcinoma Laminin-binding Protein, LAMBR, Laminin receptor 1, Laminin-binding Protein precursor p40, LAMR1, LBP/p40, LRP/LR, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, Ribosomal Protein SA (RPSA)

    Gene Symbol: RPSA

    分子量

    37-67 kDa

    基因ID

    3921

    UniProt

    P08865

    途径

    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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