RNLS 抗体 (AA 34-235) (CF®647)
Quick Overview for RNLS 抗体 (AA 34-235) (CF®647) (ABIN7659539)
抗原
See all RNLS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 34-235
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原理
- Renalase (Renal Cell Marker) (RNLS/1940), CF647 conjugate
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产品特性
- Renalase is a 342 amino acid FAD-dependent amine oxidase that is highly expressed in kidney and is expressed at a lower level in heart, skeletal muscle and small intestine. Renalase is secreted in the blood by the kidney and it is thought to regulate cardiac function and systemic blood pressure. It is also suggested that Renalase functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. Individuals with chronic kidney disease and end-stage renal disease have markedly reduced levels of plasma Renalase than healthy individuals. Infusion of Renalase in animal models causes decrease in heart rate, cardiac contractility and blood pressure. Two isoforms of Renalase exist due to alternative splicing events. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human RNLS protein fragment (around aa 34-235)
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亚型
- IgG2b, kappa
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anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (AA 160-319) antibody
RNLS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (AA 18-342) antibodyRNLS 适用: 人 WB 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (AA 68-242) antibodyRNLS 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1C11E8 unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (AA 201-300) antibodyRNLS 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (AA 18-342) antibodyRNLS 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (Internal Region) antibodyVerified RNLS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (C-Term) antibodyRNLS 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (Middle Region) antibodyRNLS 适用: 人, 小鼠, 大鼠, 马, Pig, 兔, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) antibodyRNLS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Renalase, FAD-Dependent Amine Oxidase (RNLS) (AA 1-342) antibodyRNLS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry
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说明
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Positive Control: 293T Cells. Heart or Kidney
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))
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别名
- Renalase
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背景
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Synonyms: Chromosome 10 open reading frame 59, MAO C, MAO-C, Monoamine oxidase-C, Renalase, Renalase FAD dependent amine oxidase, RNLS
Gene Symbol: RNLS
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分子量
- 38 kDa
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基因ID
- 55328
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UniProt
- Q5VYX0
抗原
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