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Prolactin Receptor 抗体 (CF®740)

This CF®740-conjugated 小鼠 单克隆 anti-Prolactin Receptor antibody (Clone B6-2 PRLR742) specifically detects Prolactin Receptor in IHC 和 IHC (fp). The antibody is reactive with 人 samples.
产品编号 ABIN7659178
发货至: 中国
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Quick Overview for Prolactin Receptor 抗体 (CF®740) (ABIN7659178)

抗原

See all Prolactin Receptor (PRLR) 抗体
Prolactin Receptor (PRLR)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Prolactin Receptor antibody is conjugated to CF®740

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

B6-2 PRLR742
  • 原理

    Prolactin Receptor(B6.2 + PRLR742), CF740 conjugate

    产品特性

    This antibody recognizes a protein of 70 kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Semi-purified human prolactin receptor (B6.2), Recombinant human prolactin receptor (PRLR742)

    亚型

    IgG
  • 应用备注

    Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunofluorescence: 0.5-1 μg/mL. Immunohistology formalin-fixed 0.5-1 μg/mL. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. Flow Cytometry 0.5-1 μg/million cells/0.1 mL. Optimal dilution for a specific application should be determined by user

    说明

    Positive Control: Testicular Carcinoma

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % rBSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Prolactin Receptor (PRLR)

    别名

    Prolactin Receptor

    背景

    Synonyms: CPRLP|hPRL receptor|hPRLrI|Lactogen receptor|OPR|Pr-1|Pr-3|PRL-R|Prolactin receptor delta 7/11|RATPRLR|Secreted prolactin binding protein|Truncated testis-specific box 1-C prolactin receptor

    Gene Symbol: PRLR

    分子量

    70 kDa

    基因ID

    5618

    UniProt

    P16471

    途径

    JAK/STAT Signaling, Response to Growth Hormone Stimulus
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