Prolactin Receptor 抗体
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Quick Overview for Prolactin Receptor 抗体 (ABIN6940404)
抗原
See all Prolactin Receptor (PRLR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Prolactin Receptor (PRL-R) Antibody
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特异性
- It recognizes a protein of 70 kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Semi-purified human full-length prolactin receptor
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亚型
- IgG1, kappa
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应用备注
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Positive Control: Breast, placenta, liver or pancreas.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin/paraffin tissues requires digestion of tissue sections with pepsin at 1 mg/mL Tris-HCl, pH 2.0 for 15 min at RT or 10 min at 37C.)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. ,Non-hazardous. No MSDS required.
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有效期
- 24 months
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- Prolactin Receptor (PRLR)
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别名
- PRLR
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背景
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CPRLP, hPRL receptor, hPRLrI, Lactogen receptor, OPR, Pr-1, Pr-3, PRL-R, Prolactin receptor delta 7/11, RATPRLR, Secreted prolactin binding protein, Truncated testis-specific box 1-C prolactin receptor
Breast, liver or pancreas, Placenta
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分子量
- 70kDa
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基因ID
- 5618, 368587
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UniProt
- P16471
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途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus
抗原
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