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Prohibitin 抗体 (AA 167-261) (CF®405S)

This anti-Prohibitin antibody is a 小鼠 单克隆 antibody detecting Prohibitin in WB, IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7659015
发货至: 中国

Quick Overview for Prohibitin 抗体 (AA 167-261) (CF®405S) (ABIN7659015)

抗原

See all Prohibitin (PHB) 抗体
Prohibitin (PHB)

适用

  • 243
  • 66
  • 63
  • 11
  • 8
  • 6
  • 6
  • 6
  • 5
  • 5
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 132
  • 117
小鼠

克隆类型

  • 145
  • 104
单克隆

标记

  • 104
  • 22
  • 11
  • 11
  • 11
  • 11
  • 11
  • 11
  • 10
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Prohibitin antibody is conjugated to CF®405S

应用范围

  • 187
  • 167
  • 110
  • 55
  • 45
  • 28
  • 19
  • 18
  • 17
  • 14
  • 13
  • 6
  • 6
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

PHB-3228
  • 抗原表位

    • 121
    • 16
    • 15
    • 9
    • 9
    • 8
    • 8
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 167-261

    原理

    Prohibitin (Mitochondrial Marker)(PHB/3228), CF405S conjugate

    产品特性

    Recognizes a protein of 30 kDa which is identified as Prohibitin, an evolutionarily conserved protein with homologues found in yeast to man. It is located in the inner membrane of mitochondria. Although prohibitin mRNA and protein expression occurs throughout the cell cycle, maximum levels are detected during the G1/S phase transition and minimum levels are seen in S phase and the G2/mitosis boundary. Prohibitin is located exclusively in the mitochondria with the highest concentration on the inner membrane. Prohibitin is an ideal mitochondrial marker. It shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization, and tumor suppression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human PHB protein fragment (aa167-261)

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: Liver, Kidney, Heart or Endometrium (IHC).

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    Prohibitin (PHB)

    别名

    Prohibitin

    背景

    Synonyms: Epididymis luminal protein 215, Epididymis secretory sperm binding protein Li 54e, HEL 215, HEL S 54e, PHB, PHB1, Prohibitin

    Gene Symbol: PHB

    分子量

    ~30 kDa

    基因ID

    5245

    UniProt

    P35232

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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