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PDLIM1 抗体 (CF®568)

This anti-PDLIM1 antibody is a 小鼠 单克隆 antibody detecting PDLIM1 in IHC 和 IHC (fp). Suitable for 人.
产品编号 ABIN7658514
发货至: 中国

Quick Overview for PDLIM1 抗体 (CF®568) (ABIN7658514)

抗原

See all PDLIM1 抗体
PDLIM1 (PDZ and LIM Domain 1 (PDLIM1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This PDLIM1 antibody is conjugated to CF®568

应用范围

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Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

CPTC-PDLIM1-1
  • 原理

    PDZ and LIM Domain 1(CPTC-PDLIM1-1), CF568 conjugate

    产品特性

    CLP36, also known as PDLIM1, CLIM1 or Elfin, is a 329 amino acid cytoplasmic protein that associates with actin stress fibers at the cytoskeleton. Expressed at high levels in skeletal muscle and heart and at lower levels in colon, small intestine, spleen, lung, placenta, kidney, liver, thymus and pancreas, CLP36 functions as a cytoskeletal protein that is thought to act as an adaptor, bringing target proteins to the cytoskeleton. Specifically, CLP36 interacts with Clik1 (-actinin-1, thereby facilitating the association of Clik1 with actin stress fibers. CLP36 contains one PDZ domain and one LIM zinc-binding domain through which it conveys its protein-protein binding capabilities. Human CLP36 shares 88 % sequence similarity with its rat counterpart, suggesting a conserved function between species. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human full-length PDLIM1 protein

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: HepG2 cells and extracts from Jurkat. Human heart, colon or spleen.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    PDLIM1 (PDZ and LIM Domain 1 (PDLIM1))

    别名

    PDZ and LIM Domain 1

    背景

    Synonyms: C terminal LIM domain protein 1, carboxy terminal LIM domain protein 1, CLIM1, CLP36, Elfin, Enigma antibody, Enigma homolog antibody, hCLIM1, PDLIM1, PDZ and LIM domain 1

    Gene Symbol: PDLIM1

    分子量

    36 kDa

    基因ID

    9124

    UniProt

    O00151
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