Recombinant pan Keratin 抗体 (pan) (Biotin)
Quick Overview for Recombinant pan Keratin 抗体 (pan) (Biotin) (ABIN7658454)
抗原
See all pan Keratin (panKRT) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pan
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原理
- Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), Biotin conjugate
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产品特性
- Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67 kDa (CK1); 64 kDa (CK3); 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 52 kDa (CK8); 56.5 kDa (CK10); 50 kDa (CK14); 50 kDa (CK15); 48 kDa (CK16); 40 kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It may be useful to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has high sensitivity in the recognition of epithelial cells and carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant full-length human KRT76 and KRT77 proteins
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亚型
- IgG
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anti-pan Keratin (panKRT) antibody
panKRT 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-pan Keratin (panKRT) antibodypanKRT 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 7H8C4 unconjugated
anti-pan Keratin (panKRT) (AA 331-430) antibodypanKRT 适用: 人, 大鼠 IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-pan Keratin (panKRT) (pan) antibodypanKRT 适用: 人, 大鼠, 小鼠 WB, IHC (p), ELISA 宿主: 兔 Polyclonal unconjugated
anti-pan Keratin (panKRT) antibodypanKRT 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-000R unconjugated Recombinant Antibody
anti-pan Keratin (panKRT) antibodypanKRT 适用: 人, 大鼠, 小鼠, Cow, 猴, 犬, 兔, 小鸡 IF, FACS, WB, IHC (p) 宿主: 小鼠 Monoclonal AE1-AE3 unconjugated
anti-pan Keratin (panKRT) antibodyGMP Grade panKRT 适用: 人 FACS 宿主: 小鼠 Monoclonal MCK457 unconjugated
anti-pan Keratin (panKRT) antibody (iFluor™488)GMP Grade panKRT 适用: 人 FACS 宿主: 小鼠 Monoclonal MCK457 iFluor™488
anti-pan Keratin (panKRT) antibodypanKRT 适用: 人, 大鼠, 小鼠, Cow, Pig, Frog, 豚鼠, 山羊, Marmoset IF, FACS, WB, IHC, StM 宿主: 小鼠 Monoclonal SPM583 unconjugated
anti-pan Keratin (panKRT) antibodypanKRT 适用: 人, 大鼠 IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal KRTL-1077-KRTH-1076 unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: Skin, Adeno- or Squamous carcinomas
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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