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Recombinant pan Keratin 抗体 (basic) (CF®640R)

This CF®640R-conjugated 兔 单克隆 anti-pan Keratin antibody (Clone KRTH-2147R) specifically detects pan Keratin in IF, IHC 和 IHC (fp). The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7658401
发货至: 中国
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Quick Overview for Recombinant pan Keratin 抗体 (basic) (CF®640R) (ABIN7658401)

抗原

See all pan Keratin (panKRT) 抗体
pan Keratin (panKRT)

抗体类型

Recombinant Antibody

适用

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人, 大鼠, 小鼠

宿主

  • 96
  • 69
  • 3

克隆类型

  • 130
  • 38
单克隆

标记

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This pan Keratin antibody is conjugated to CF®640R

应用范围

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Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

克隆位点

KRTH-2147R
  • 抗原表位

    • 30
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    • 15
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    • 1
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    • 1
    basic

    原理

    Cytokeratin, Basic (Type II or HMW)(KRTH/2147R), CF640R conjugate

    产品特性

    This antibody recognizes CK1, CK5, CK10 and CK14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. This MAb shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands, there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this antibody. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. This antibody has also been useful in separating benign from malignant intraductal breast proliferations. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Solubilized keratin extract from human stratum corneum

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Positive Control: MCF-7, PC12 cells, Skin, Prostate carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS, 0.1 % BSA, 0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light

    储存条件

    4 °C

    储存方法

    Stable at room temperature or 37°C for 7 days.

    Protect from light

    Store at 2 to 8°C. Protect fluorescent conjugates from light

    有效期

    24 months
  • 抗原

    pan Keratin (panKRT)

    别名

    Keratin

    背景

    Synonyms: KRT2B, KRT2P, HUMCYT2A, Keratin, type II Cytoskeletal 2 oral, K76, Keratin 2p (K2P), Keratin-76, Cytokeratin-2P (CK-2P, Type-II Keratin Kb9

    Gene Symbol: KRT76

    Tissue Expression: Epidermal cells|Epithelial cells

    分子量

    50-67 kDa

    基因ID

    51350

    UniProt

    Q01546
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