OLIG2 抗体 (AA 1-141) (CF®647)
Quick Overview for OLIG2 抗体 (AA 1-141) (CF®647) (ABIN7658218)
抗原
See all OLIG2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-141
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原理
- OLIG2 (Marker of Glial Brain Tumors) (OLIG2/2400), CF647 conjugate
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产品特性
- Olig2, a basic helix-loop-helix transcription factor, is involved in oligodendroglial specification. Olig2 expression has been reported in most glial tumors, such as oligodendrogliomas and astrocytomas. Although more than half of glioblastomas are positive for Olig2, expression is very weak in terms of both percentage of labeled cells and intensity. No Olig2 expression has been found in the non-glial tumors including neuro-epithelial tumors, ependymomas, sub-ependymomas, medulloblastomas, and non-neuroepithelial tumors, such as CNS lymphomas, meningiomas, schwannomas, atypical teratoid / rhabdoid tumor, and haemangioblastomas. Compared to the strong staining seen in glioma samples, a weak expression is observed in non-tumoral brain tissue (gliosis).Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant fragment of human OLIG2 protein (around aa 1-141)
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亚型
- IgG1, kappa
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anti-Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) (C-Term) antibody
OLIG2 适用: 人, 小鼠, 大鼠, 豚鼠, 犬, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) (AA 2-78) antibodyOLIG2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3C9 unconjugated
anti-Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) (AA 200-300) antibodyOLIG2 适用: 人 IHC (f) 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
anti-Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) antibodyOLIG2 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) (N-Term) antibodyOLIG2 适用: 人, 小鼠, 大鼠, 斑马鱼, 豚鼠, 犬, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) antibodyOLIG2 适用: 人, 小鼠, 大鼠, 小鸡 WB, IHC, ELISA, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) (AA 2-78) antibodyOLIG2 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 3D7 unconjugated
anti-Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) antibodyMicroarray verified OLIG2 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB264610 unconjugated
anti-Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) (AA 1-141) antibodyOLIG2 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal OLIG2-2400 unconjugated
anti-Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) (AA 1-80) antibodyOLIG2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 1-2 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user
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说明
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Positive Control: THP-1 cells. Astrocytoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, 0.1 % BSA, 0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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储存条件
- 4 °C
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储存方法
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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有效期
- 24 months
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- OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
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别名
- OLIG2
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背景
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Synonyms: Basic helix loop helix protein class B1 (bHLHB1), basic helix-loop-helix protein 19 (bHLHe19), OLIG2, Oligodendrocyte lineage transcription factor 2, Oligodendrocyte specific bHLH transcription factor 2, Oligodendrocyte transcription factor 2, Protein kinase C-binding protein 2 (PRKCBP2), RACK17
Gene Symbol: OLIG2
Tissue Expression: Glia
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分子量
- 30-40 kDa
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基因ID
- 10215
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UniProt
- Q13516
抗原
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